Biography

13 years of experience working with high-dimensional genomic data, implementing new methods to interpret data for decision-making in research/development projects. Built and managed the Illumina and Nanopore sequencing capabilities in 3 companies applying the technology to platforms for target discovery, gene editing, SHAPE-MaP and MoA projects. 8 years studying neurodegenerative diseases, and 5 years working in Oncology field. Experience harmonizing thousands of multi-omics data in a unique dashboard for preclinical and clinical project stages. Accessed controlled raw data from NIH protected datasets (i.e. TCGA). Built 6 bioinformatics packages commonly used nowadays by the open-source community. Managed a team of five scientists and engineers to build and maintain compute infrastructure, reproducible analyses and data sharing with interactive web-apps. Managed efficiently cloud computing and storage infrastructure with AWS services, PostIt (Rstudio) and Nextflow Seqera.

Community

JOSS editor. Join our women in bioinformatics in Boston area.

My tools

Tool	Downloads
mirtop
seqcluster
seqclusterViz
isomiRs
DEGreport

contributed to: nf-core, bcbio-nextgen, cloudbiolinux, bcbioRNASeq, bioconda, multiqc

Interests

Target Discovery and Patient Stratification in Oncology and Neurodegeneration
Sequencing-based Platforms, Multi-Omic Modelling and Genomic Visualization

Education

PhD in Biomedicine, 2011

Pompeu Fabra University
Ms in Bioinformatics, 2008

Pompeu Fabra University
BSc in Biochemistry, 2005

University of Granada

Skills

Genomics Data AI Modelling

Scientific Strategy

Complex Data Visualization

AWS Infrastructure

NGS

Experience

Director, Head of Computational Biology

NextRNA Therapeutics

May 2021 – Present Cambridge

Responsibilities include:

Preparing slides and data packages for partners and BoD
Leading the in-silico Target discovery pipelines integrating genomic data
Leading RNA-Protein interaction prediction from high-throughput sequencing data
Leading visualization plarforms in the discovery program
Mantaining and evolving bioinformatic infrastructure to ensure reproducibility and scalability under budget restrictions
Multi-omics analysis of (genomics and clinical) data available through TCGA, PCAWG, and other type of controlled data
Senior Manager and Mentor

Principal Scientist in Computational Biology

Axcella Health

Sep 2020 – Apr 2021 Cambridge

Responsibilities include:

Leading R&D pipelines with computational strategies
Analysing metabolimic/transcriptomic data
Leading visualization plarform to boost biological interpretation
Developing bioinformatic infrastructure to ensure reproducibility and scalability
Senior Manager and Mentor

Senior Computational Biologist

eGenesis Bio

Sep 2019 – Sep 2020 Cambridge

Responsibilities include:

Leading genome editing QC pipeline
Analysing genomic/transcriptomic data
Developing bioinformatic tools
Data structure architect
Managing knowledge-base platform
Mentoring

Research Scientist

Harvard Chan School

Jun 2017 – Apr 2019 Boston

Responsibilities include:

Leading computational analysis under a multi-group collaboration with Boehringer-ingelheim for 3 years
Leading miRNA transcriptomic open project
Analysing genomic data
Developing bioinformatic tools
Managing knowledge-base platform
Mentoring

Research Associate

Harvard Chan School

May 2014 – Jun 2017 Boston

Analyzed sequencing data in pathogenic conditions. Developed bioinformatics tools for sequencing data (RNA-seq, smallRNA-seq, ChIP-seq, ATAC-seq).

Post-doctoral fellow

Institute of Biotechnology and Biomedicine

Feb 2013 – Apr 2014 Barcelona

Detected de-novo transcripts as effect of inversion in the HapMap population.Expression quantitive trait loci analysis of inversion in the HapMap population.