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SOXB1 Transcription Factors
Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions.
Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the frequency of reprogramming …
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