Humans

Genomic analyses identify molecular subtypes of pancreatic cancer
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 …
P Bailey, D K Chang, K Nones, A L Johns, A M Patch, M C Gingras, D K Miller, A N Christ, T J Bruxner, M C Quinn, C Nourse, L C Murtaugh, I Harliwong, S Idrisoglu, S Manning, E Nourbakhsh, S Wani, L Fink, O Holmes, V Chin, M J Anderson, S Kazakoff, C Leonard, F Newell, S Wood, Q Xu, P J Wilson, N Cloonan, K S Kassahn, D Taylor, K Quek, A Robertson, L Pantano, L Mincarelli, L N Sanchez, L Evers, J Wu, M Pinese, M J Cowley, M D Jones, E K Colvin, A M Nagrial, E S Humphrey, L a Chantrill, A Mawson, J Humphris, A Chou, M Pajic, C J Scarlett, A v Pinho, M Giry-Laterriere, I Rooman, J S Samra, J G Kench, J a Lovell, N D Merrett, C W Toon, K Epari, N Q Nguyen, A Barbour, N Zeps, K Moran-Jones, N B Jamieson, J S Graham, F Duthie, K Oien, J Hair, R Grutzmann, A Maitra, C a Iacobuzio-Donahue, C L Wolfgang, R a Morgan, R T Lawlor, V Corbo, C Bassi, B Rusev, P Capelli, R Salvia, G Tortora, D Mukhopadhyay, G M Petersen, Initiative Australian Pancreatic Cancer Genome, D M Munzy, W E Fisher, S a Karim, J R Eshleman, R H Hruban, C Pilarsky, J P Morton, O J Sansom, A Scarpa, E a Musgrove, U M Bailey, O Hofmann, R L Sutherland, D a Wheeler, A J Gill, R a Gibbs, J v Pearson, N Waddell, A v Biankin, S M Grimmond
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The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes.
At the end of mammalian sperm development, sperm cells expel most of their cytoplasm and dispose of the majority of their RNA. Yet, …
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Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity
The global rise in obesity has revitalized a search for genetic and epigenetic factors underlying the disease. We present a Drosophila …
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A highly expressed miR-101 isomiR is a functional silencing small RNA.
BACKGROUND: MicroRNAs (miRNAs) are short non-coding regulatory RNAs that control gene expression usually producing translational …
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Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor.
BACKGROUND: Epidermal Growth Factor (EGF) plays an important function in the regulation of cell growth, proliferation, and …
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A non-biased framework for the annotation and classification of the non-miRNA small RNA transcriptome.
MOTIVATION: Recent progress in high-throughput sequencing technologies has largely contributed to reveal a highly complex landscape of …
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SeqBuster, a bioinformatic tool for the processing and analysis of small RNAs datasets, reveals ubiquitous miRNA modifications in human embryonic cells
High-throughput sequencing technologies enable direct approaches to catalog and analyze snapshots of the total small RNA content of …
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Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions.
Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying …
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ProSeeK: A web server for MLPA probe design
Background: The technological evolution of platforms for detecting genome-wide copy number imbalances has allowed the discovery of an …
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Genome assembly comparison identifies structural variants in the human genome.
Numerous types of DNA variation exist, ranging from SNPs to larger structural alterations such as copy number variants (CNVs) and …
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