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Single-cell cloning of human T-cell lines reveals clonal variation in cell death responses to chemotherapeutics.
Genetic modification of human leukemic cell lines using CRISPR-Cas9 has become a staple of gene-function studies. Single-cell cloning …
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Sex Differences in Adrenal Bmal1 Deletion-Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice.
The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock …
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A High-Throughput Screening Identifies MicroRNA Inhibitors That Influence Neuronal Maintenance and/or Response to Oxidative Stress.
Small non-coding RNAs (sncRNAs), including microRNAs (miRNAs) are important post-transcriptional gene expression regulators relevant in …
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Multi omics analysis of fibrotic kidneys in two mouse models.
Kidney fibrosis represents an urgent unmet clinical need due to the lack of effective therapies and an inadequate understanding of the …
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Evolutionary and functional impact of common polymorphic inversions in the human genome
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Sex-dependent changes in miRNA expression in the bed nucleus of the stria terminalis following stress
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Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API
Background: MicroRNAs (miRNAs) are small RNA molecules (̃22 nucleotide long) involved in post-transcriptional gene regulation. Advances …
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The circulating metabolome of human starvation
The human adaptive starvation response allows for survival during long-term caloric deprivation. Whether the physiology of starvation …
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Circulating miRNAs, isomiRs and small RNA clusters in human plasma and breast milk
Circulating small RNAs, including miRNAs but also isomiRs and other RNA species, have the potential to be used as non-invasive …
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bcbioRNASeq: R package for bcbio RNA-seq analysis
RNA-seq analysis involves multiple steps from processing raw sequencing data to identifying, organizing, annotating, and reporting …
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